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Alli weight-loss pill: Does it work?

How is Alli taken?

One 60-milligram Alli pill is taken within an hour of a fat-containing meal up to three times a day. Daily fat intake should be distributed over the three main meals and should be no more than 30 percent of total calories. The manufacturer recommends a fat intake of about 15 grams a meal.

If you eat a meal that contains no fat, then you don't need a dose of Alli. If you take Alli with a high-fat meal, you will likely experience more-severe gastrointestinal side effects.

Alli can reduce the absorption of fat-soluble nutrients, including beta carotene and vitamins A, D, E and K. Take a multivitamin at bedtime and at least two hours after your last dose of Alli.

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